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These scores vary in direct proportion to estrogen levels throughout the menstrual cycle, pregnancy, and menopause.Furthermore, estrogens when administered shortly after natural or surgical menopause prevents decreases in verbal memory.

The three major naturally occurring estrogens in women are estrone (E1), estradiol (E2), and estriol (E3).

While estrogens are present in both men and women, they are usually present at significantly higher levels in women of reproductive age.

They promote the development of female secondary sexual characteristics, such as breasts, and are also involved in the thickening of the endometrium and other aspects of regulating the menstrual cycle.

In males, estrogen regulates certain functions of the reproductive system important to the maturation of sperm Estrogens are responsible for the development of female secondary sexual characteristics during puberty, including breast development, widening of the hips, and female fat distribution.

Conversely, androgens are responsible for pubic and body hair growth, as well as acne and axillary odor.

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