After leaving the series, she nevertheless joined the other principal Lost cast members of season 2 onstage at the 12th Screen Actors Guild Awards where Lost won the award for Outstanding Performance by an Ensemble in a Drama Series.In 2007, she starred in The Jane Austen Book Club, based on Karen Joy Fowler's novel of the same name.While struggling financially, she landed her first role as the title character in the web-based video series Rachel's Room in 2001.She went on to earn a Young Artist Award nomination in 2002 with her portrayal of 15-year-old murder victim Martha Moxley in the television movie Murder in Greenwich.
She reprised the role in Taken 2 (2012) and Taken 3 (2014).
In December 2012, it was announced Grace would be making her Broadway debut in Picnic.
The play opened for previews on December 14, running at the American Airlines Theatre.
She went on to feature in minor roles on the television series CSI: Miami, The Lyon's Den, Miracles, Like Family, Cold Case and Law & Order: Special Victims Unit, and the films Twelve Mile Road and Creature Unknown. Her character was killed in the season's eighth episode, "Collision", when the series' writers began to feel that the character's "story avenues [were] limited".
Executive producer Carlton Cuse said that Grace's departure from the show was "sort of a win-win" as she was eager to enter a full-time career in film.